Epitalon and Vision – Extensive Research – african 2nice Internet upates.
The Epitalon peptide (also known as Epithalamin and Epithalon) stands out among the various peptides under investigation. Researchers are interested in learning more about its possible uses. Despite initial research, further study is needed to determine the peptide’s mode of action.
It comprises the four synthetic amino acids glutamic acid, glycine, aspartic acid, and alanine, making it a tetrapeptide. C14H22N4O9 is its chemical formula, and its molecular weight is about 390.35 g/mol. The pineal gland secretes a hormone called Epithalamin, which is considered to be chemically identical to the synthetic Epitalon peptide.
By increasing the hypothalamus’s sensitivity to its natural hormone, researchers may correct the circadian rhythm in animal test subjects by manipulating their melatonin levels. Studies suggest Epitalon has exhibited some potential throughout anti-aging and life-extension evaluations on animals. Prof. Vladimir Khavinson of Russia spent more than 35 years researching Epitalon after discovering it. His research suggested that Epitalon might support sleep function, mitigate cancer cell proliferation, and have an anti-aging impact.
Epitalon Peptide Research
Researchers have identified numerous possible properties of Epitalon since they began giving peptides to test subjects. According to researchers, the shortening of telomeres is a known contributor to cellular and organ age. Research suggests Epitalon seems to cause an extension of telomere in exposed cells, which may slow, stop, or even reverse the consequences of aging at the cellular level. Studies have suggested that cells exposed to the peptide may regenerate and heal. [i]
When examined closely under a microscope, cells from animals have suggested that correction may occur, at least in part, at the level of the subject’s DNA. This suggestion raises intriguing possibilities for the outcomes of studies examining cell repair and regeneration. Researchers have hypothesized that Epitalon may manage abnormalities inside the reproductive systems of female rats and the subject’s melatonin and cortisol levels. As a result of this control, scientists have better understood how cells govern themselves. It has been speculated that Epitalon may slow the growth of tumors and even repair some of the harm done to the tumors during their development. [ii]
Epitalon Peptide, Insomnia, and Melatonin
The pineal gland regulates and maintains melatonin levels. Research has indicated that blood melatonin levels decrease significantly over time.
Scientists consider melatonin a hormone that regulates the neurological, endocrine, and immunological systems. Incorporating melatonin appears to exhibit a geroprotective action. However, this action may exacerbate potential downstream impacts, such as neoplastic development. Because of this, researchers have been looking for methods to promote endogenous melatonin production effectively. [v]
Epitalon Peptide and Aging
Epitalon-exposed test subjects seem to have a longer lifespan than their non-exposed controls, as the researchers of various test studies suggested. The findings of several studies have theorized that the death rate in certain subjects has been decreased by as much as half, increasing their longevity by roughly 1.5 times compared to those who were given a placebo. Long-lived mice exposed to Epitalon cells appeared to live cancer-free for far longer than their control group counterparts that had gotten a placebo.
Researchers suggest through these studies that Epitalon may stimulate the development of telomerase, a natural enzyme that assists in the replication of telomeres in cells. DNA telomeres serve as a safeguard against the degradation of genetic material. Scientists consider the shortening of chromosomes during cell division to be a direct outcome of telomere function. Telomeres shorten every time a cell divides, explaining why aging is linked to cognitive decline, cardiovascular disease, and death. [vi]
By deliberately activating telomerase, cells may be able to increase beyond their expected lifespan. This might reverse the aging process by improving cell health and reproduction thanks to longer telomere strands. [iv]
Epitalon Peptide and Cancer
Researchers hypothesize that Epitalon may stimulate melatonin release, slowing cancer cell spread and reducing tumor growth. The proposed link between the pineal gland and cancer provides insight into this phenomenon. Epitalon appears to promote melatonin (a hormone) secretion from the pineal gland. Research suggests that melatonin may inhibit the formation of malignant tumors (in a variety of organs). [iii]
Epitalon Peptide and Sleep
Studies suggest the hormone melatonin may be secreted by the pineal gland in response to stimulation from the Epitalon peptide. Epitalon’s potential to expose and stimulate the pineal gland may increase melatonin secretion and improve sleep quality.
Epitalon Peptide and Vision
Epitalon has been hypothesized to increase telomerase production, which might lengthen and fortify DNA telomeres. This potential impact may prevent cell death or apoptosis and may also delay the onset of age-related illnesses.
The peptide has been speculated to have antioxidant capabilities, which may mitigate the instances of free radicals. Scientists consider oxygen-free radicals to be degenerative disorders, and this process may eliminate them.
Researchers have inferred that Epitalon may maintain functional retinal integrity in animals with inherited Retinitis Pigmentosa. It appeared to improve the eyesight of subjects with pigmentary retinal degeneration.
More investigation is required to explore its potential in scientific research, and these studies must continue. Only academic and scientific institutions are allowed to use Epitalon peptides. If you are a licensed professional interested in buying peptides for your clinical studies, visit this website. Please note that none of the items mentioned are approved for human or animal consumption. Clinical research chemicals are only for in-vitro and in-lab use. Any kind of physical introduction is illegal. Only licensed academics and working scientists may make purchases. The content of this article is intended only for educational purposes.
References
[i] Anisimov VN, Khavinson VKh, Alimova IN, et al. Epithalon decelerates aging and suppresses the development of breast adenocarcinomas in transgenic her-2/neu mice. Bull Exp Biol Med, 2002.
[ii] Kossoy G, Anisimov VN, Ben-Hur H, et al. Effect of the synthetic pineal peptide epitalon on spontaneous carcinogenesis in female C3H/He mice. In Vivo, 2006.
[iii] Alimova IN, Bashurin DA, Popovich IG, et al. Effect of Epitalon and Vilon treatment on mammary carcinogenesis in transgenic erbB-2/NEU mice. Vopr Onkol, 2002.
[iv] Khavinson VKh. Peptides and Ageing. Neuro Endocrinol Lett, 2002.
[v] Kozina LS, Arutjunyan AV, Khavinson VKh. Antioxidant properties of geroprotective peptides of the pineal gland. Arch Gerontol Geriatr, 2007.
[vi] Khavinson VKh, Bondarev IE, Butyugov AA. Epithalon peptide induces telomerase activity and telomere elongation in human somatic cells. Bull Exp Biol Med, 2003.
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